Vehicle-induced multiple trauma: Serum lactate level and prognosis

Document Type : Original Article

Authors

1 Student Research Committee, Babol University of Medical Sciences, Babol, Iran

2 Research and Planning Unit, Pre Hospital Emergency Organization and Emergency Medical Service Center, Babol University of Medical Sciences, Babol, Iran

3 Department of General Surgery, Shahid Beheshti Hospital, Babol University of Medical Sciences, Babol, Iran

4 Department of Epidemiology and Biostatics, Babol University of Medical Sciences, Babol, Iran

5 Students Scientific Research Center, School of Nursing and Midwifery, Tehran University of Medical Sciences, Tehran; Research and Planning Unit, Pre Hospital Emergency Organization and Emergency Medical Service Center, Babol University of Medical Sciences, Babol, Iran

10.4103/atr.atr_74_21

Abstract

Background and Objectives: Early assessment of the severity and prognosis of multiple trauma injuries is crucial for the improvement of prognosis. Therefore, defining the parameters related to mortality and severity of multiple trauma injuries needs to be considered. The current study aims to investigate the serum lactate level and prognosis of these patients. Materials and Methods: This is a cross-sectional study conducted on 150 motor-vehicle-induced multiple trauma patients who were admitted to the Babol Trauma Center for 15 months. The serum lactate level was measured at the time of admission, 24 h, and 72 h after admission. The outcome of the patients was evaluated as death, hospitalization, or discharge. Results: Overall, 150 motor vehicle-induced trauma patients were enrolled in the study. Hyperlactatemia was seen in 33 (22%) patients in 24 h and 78 (52%) patients in 72 h after admission (P < 0.001). There was a clinically significant correlation between lactate level at the time of admission and the outcome of the patients (5.22 ± 3.41 expired, 2.69 ± 1.67 hospitalized, and 1.83 ± 1.09 discharged, P < 0.00). There was a clinically significant correlation between the serum lactate level at 24 h after admission and the outcome of the patients (6.81 ± 3.51 expired, 1.35 ± 0.79 hospitalized, and 0.83 ± 0.23 discharged, P < 0.001). There was also a clinically significant correlation between the outcome of the patients (discharge or hospitalization, or death) and the serum lactate level at the time of the admission and 24 h after the admission (P = 0.035). Conclusions: The baseline lactate, the lactate level at 24 h after admission, and the difference between these two can be used as a prognostic factor in the evaluation of multiple trauma patients. It is suggested to check the difference between the serum lactate level at the time of admission and 24 h later in trauma centers.

Keywords


1.
Spahn DR, Bouillon B, Cerny V, Duranteau J, Filipescu D, Hunt BJ, et al. The European guideline on management of major bleeding and coagulopathy following trauma 2019;23:98.  Back to cited text no. 1
    
2.
Datobar H, Alijanpour S, Khafri S, Jahani M, Naderi R. Patient's Satisfaction of Emergency Department Affiliated Hospital of Babol University of Medical Sciences in 2013 -14. JBUMS 2016;18:56-62. Available from: http://jbums.org/article-1-5626-en.html. [Last accessed on 2021 Mar 14].  Back to cited text no. 2
    
3.
Poitzman A, Makaroum T, Slasky S. Prospective study of CT in initial management of blunt abdominal trauma. J Trauma 1996;26:585-89.  Back to cited text no. 3
    
4.
Nasr A, Alimohammadi N, Isfahani MN, Alijanpour S. Development and domestication of a clinical guideline for pharmacological pain management of trauma patients in prehospital setting. Arch Trauma Res 2019;8:110-7.  Back to cited text no. 4
  [Full text]  
5.
Guyette FX, Meier E, Kerby J, Williams C, Schlamp R, Wand R, et al. Prehospital Lactate for Identification of the Need for Resuscitative Care in Trauma Patients Transported by Air. Circulation 2014;130(Suppl 2):3.  Back to cited text no. 5
    
6.
Callaway DW, Shapiro NI, Donnino MW, Baker C, Rosen CL. Serum Lactate and Base Deficit as Predictors of Mortality in Normotensive Elderly Blunt Trauma Patients. The Journal of TRAUMA_ Injury, Infection, and Critical Care 2009;66:1040-4.  Back to cited text no. 6
    
7.
Caputo N, Fraser R, Paliga A, Kanter M, Hosford K, Madlinger R: Triage vital signs do not correlate with serum lactate or base deficit, and are less predictive of operative intervention in penetrating trauma patients: a prospective cohort study. Emerg Med 2013;30:546-50.  Back to cited text no. 7
    
8.
Cerovi O, Golubovi V, Spec-Marn A, Kremzar B, Vidmar G: Relationship between injury severity and lactate levels in severely injured patients. Intensive Care Med 2003;29:1300-5.  Back to cited text no. 8
    
9.
Jo S, Lee JB, Jin YH, Jeong T, Yoon J, Choi SJ, et al. Comparison of the trauma and injury severity score and modified early warning score with rapid lactate level (the ViEWS-L score) in blunt trauma patients. European Journal of Emergency Medicine. 2014;21(3):199-205.  Back to cited text no. 9
    
10.
Husain FA, Martin MJ, Mullenix PS, Steele SR, Elliott DC: Serum lactate and base deficit as predictors of mortality and morbidity. Am J Surg 2003;185:485-91.  Back to cited text no. 10
    
11.
Parsikia A, Bones K, Kaplan M, Strain J, Leung PS, Ortiz J, et al. The predictive value of initial serum lactate in trauma patients. Shock 2014;42:199-204.  Back to cited text no. 11