Distal femur fracture fixation failure: The role of distal femur replacement in a revision setting

Document Type : Original Article

Authors

Department of Orthopaedics, The Ohio State University Wexner Medical Center, Columbus, OH, USA

10.4103/atr.atr_116_20

Abstract

Introduction: Distal femur fractures are a common fracture seen in both high and low-energy traumas in young and elderly patients. The standard of care in healthy, mobile, younger patients remains open reduction and internal fixation (ORIF) through various fixation devices. However, the standard of care for comorbid and elderly patients remains unclear. In these patients, rates of nonunion vary between 6% and 20%, requiring revision surgery. Our study sought to identify patients who have gone endoprosthesis conversion to a distal femur replacement following failed ORIF. 
Methods: This descriptive study includes a total of eight patients who underwent a revision distal femoral replacement (DFR) following failure of primary distal femur ORIF and data were gathered through chart review. Patient comorbidities, demographic characteristics, hospital disposition, complications, and mortality were collected and described. 
Results: The average age of this cohort was 52.1 years, with 6 being female, and with a follow-up mean of 3.02 years. The most common medical comorbidities present in these patients at the time of ORIF were diabetes, hypertension, obesity, smoking, and renal insufficiency. 87.5% of patients were able to tolerate weight bearing following DFR conversion, compared to 62.5% tolerating weight bearing before revision. Complications requiring revision surgery occurred in 3/8 patients, which included: aseptic loosening, prosthetic joint infection, and patellar maltracking. 
Conclusion: DFR in a revision setting following acute distal femur ORIF can be an acceptable treatment options with outcomes similar to primary DFR. Further investigation is warranted to determine optimal timing and indications for primary DFR in a fracture setting.

Keywords


1.
Court-Brown CM, Caesar B. Epidemiology of adult fractures: A review. Injury 2006;37:691-7.  Back to cited text no. 1
    
2.
Hart GP, Kneisl JS, Springer BD, Patt JC, Karunakar MA. Open reduction vs. distal femoral replacement arthroplasty for comminuted distal femur fractures in the patients 70 years and older. J Arthroplasty 2017;32:202-6.  Back to cited text no. 2
    
3.
Rodriguez EK, Boulton C, Weaver MJ, Herder LM, Morgan JH, Chacko AT, et al. Predictive factors of distal femoral fracture nonunion after lateral locked plating: A retrospective multicenter case-control study of 283 fractures. Injury 2014;45:554-9.  Back to cited text no. 3
    
4.
Ricci WM, Streubel PN, Morshed S, Collinge CA, Nork SE, Gardner MJ. Risk factors for failure of locked plate fixation of distal femur fractures: An analysis of 335 cases. J Orthop Trauma 2014;28:83-9.  Back to cited text no. 4
    
5.
Bai Y, Zhang X, Tian Y, Tian D, Zhang B. Incidence of surgical-site infection following open reduction and internal fixation of a distal femur fracture: An observational case-control study. Medicine (Baltimore) 2019;98:e14547.  Back to cited text no. 5
    
6.
Blomfeldt R, Törnkvist H, Ponzer S, Söderqvist A, Tidermark J. Comparison of internal fixation with total hip replacement for displaced femoral neck fractures. Randomized, controlled trial performed at four years. J Bone Joint Surg Am 2005;87:1680-8.  Back to cited text no. 6
    
7.
Rogmark C, Carlsson A, Johnell O, Sernbo I. A prospective randomised trial of internal fixation versus arthroplasty for displaced fractures of the neck of the femur. Functional outcome for 450 patients at two years. J Bone Joint Surg Br 2002;84:183-8.  Back to cited text no. 7
    
8.
Streubel PN, Ricci WM, Wong A, Gardner MJ. Mortality after distal femur fractures in elderly patients. Clin Orthop Relat Res 2011;469:1188-96.  Back to cited text no. 8
    
9.
Salazar BP, Babian AR, DeBaun MR, Githens MF, Chavez GA, Goodnough LH, et al. Distal femur replacement versus surgical fixation for the treatment of geriatric distal femur fractures: A systematic review. J Orthop Trauma 2021;35:2-9.  Back to cited text no. 9
    
10.
Rice OM, Springer BD, Karunakar MA. Acute distal femoral replacement for fractures about the knee in the elderly. Orthop Clin North Am 2020;51:27-36.  Back to cited text no. 10
    
11.
Rosen AL, Strauss E. Primary total knee arthroplasty for complex distal femur fractures in elderly patients. Clin Orthop Relat Res 2004;425:101-5.  Back to cited text no. 11
    
12.
Haidukewych GJ, Springer BD, Jacofsky DJ, Berry DJ. Total knee arthroplasty for salvage of failed internal fixation or nonunion of the distal femur. J Arthroplasty 2005;20:344-9.  Back to cited text no. 12
    
13.
Raiss P, Edwards TB, da Silva MR, Bruckner T, Loew M, Walch G. Reverse shoulder arthroplasty for the treatment of nonunions of the surgical neck of the proximal part of the humerus (type-3 fracture sequelae). J Bone Joint Surg Am 2014;96:2070-6.  Back to cited text no. 13
    
14.
Nowak LL, Hall J, McKee MD, Schemitsch EH. A higher reoperation rate following arthroplasty for failed fixation versus primary arthroplasty for the treatment of proximal humeral fractures: A retrospective population-based study. Bone Joint J 2019;101-B:1272-9.  Back to cited text no. 14
    
15.
Mahmoud SS, Pearse EO, Smith TO, Hing CB. Outcomes of total hip arthroplasty, as a salvage procedure, following failed internal fixation of intracapsular fractures of the femoral neck: A systematic review and meta-analysis. Bone Joint J 2016;98-B:452-60.  Back to cited text no. 15
    
16.
McKinley JC, Robinson CM. Treatment of displaced intracapsular hip fractures with total hip arthroplasty: Comparison of primary arthroplasty with early salvage arthroplasty after failed internal fixation. J Bone Joint Surg Am 2002;84:2010-5.  Back to cited text no. 16
    
17.
Mabry TM, Prpa B, Haidukewych GJ, Harmsen WS, Berry DJ. Long-term results of total hip arthroplasty for femoral neck fracture nonunion. J Bone Joint Surg Am 2004;86:2263-7.  Back to cited text no. 17
    
18.
Meinberg EG, Agel J, Roberts CS, Karam MD, Kellam JF. Fracture and dislocation classification compendium-2018. J Orthop Trauma 2018;32 Suppl 1:S1-170.  Back to cited text no. 18
    
19.
Hoellwarth JS, Fourman MS, Crossett L, Goodman M, Siska P, Moloney GB, et al. Equivalent mortality and complication rates following periprosthetic distal femur fractures managed with either lateral locked plating or a distal femoral replacement. Injury 2018;49:392-7.  Back to cited text no. 19
    
20.
Consigliere P, Iliopoulos E, Ads T, Trompeter A. Early versus delayed weight bearing after surgical fixation of distal femur fractures: A non-randomized comparative study. Eur J Orthop Surg Traumatol 2019;29:1789-94.  Back to cited text no. 20
    
21.
Hussain MS, Dailey SK, Avilucea FR. Stable fixation and immediate weight-bearing after combined retrograde intramedullary nailing and open reduction internal fixation of noncomminuted distal interprosthetic femur fractures. J Orthop Trauma 2018;32:e237-40.  Back to cited text no. 21
    
22.
Poole WE, Wilson DG, Guthrie HC, Bellringer SF, Freeman R, Guryel E, et al. 'Modern' distal femoral locking plates allow safe, early weight-bearing with a high rate of union and low rate of failure: Five-year experience from a United Kingdom major trauma centre. Bone Joint J 2017;99-B:951-7.  Back to cited text no. 22
    
23.
Granata JD, Litsky AS, Lustenberger DP, Probe RA, Ellis TJ. Immediate weight bearing of comminuted supracondylar femur fractures using locked plate fixation. Orthopedics 2012;35:e1210-3.  Back to cited text no. 23
    
24.
Appleton P, Moran M, Houshian S, Robinson CM. Distal femoral fractures treated by hinged total knee replacement in elderly patients. J Bone Joint Surg Br 2006;88:1065-70.  Back to cited text no. 24
    
25.
Myers P, Laboe P, Johnson KJ, Fredericks PD, Crichlow RJ, Maar DC, et al. Patient mortality in geriatric distal femur fractures. J Orthop Trauma 2018;32:111-5.  Back to cited text no. 25